I've been playing with 2.5.0 for few days now, and 2.5.1 for a day or so. I think zooming to > e300 with the higher-degree sets is not for the faint-hearted or under-cooled, even with perturbation; the higher the power, the harder the computer has to work for even quite small numbers of iterations, and things get dense quite quickly.
This (power 6) took around half an hour to render at 3K width, and the iteration depth is only 20K:
may15_03 by
ellarien, on Flickr
Re: 0.19009200738664003775048587995178562421318906985724823420747507642375015168586422
Im: -0.57206855350604207966820504558824438694743084644648755240244611252141286546718753
Zoom: 1.49657767662E51
Iterations: 19082
I guess it would have been completely out of amateur reach without perturbation!
The upside is that in this relatively unexplored territory I feel less embarrassed about sharing my modest attempts at movies, like this power-6 zoom down to 1e70:
https://www.youtube.com/v/uff2T_0U1IU&rel=1&fs=1&hd=1The added capabilities are great, but I have found a few niggles.
-- Sometimes in a zoom-out sequence, if a glitch or minibrot falls across the edge of a frame, the parts outside the frame won't be properly solved on subsequent zoomed-out frames. Usually this can be fixed by going to that frame in the zoom sequence examination tool and doing a 'refresh', then adding references by hand.
-- Speaking of which, I love the ability to jump to a specific frame when examining the sequence, but it woud be nice if the number to enter matched the number on the kfb file instead of being the difference between that and the highest frame number.
-- It seems to cause problems (program hangs or goes into an endless loop) if I try to change the iteration limit while the calculation is running. The obvious work-around is not to do that.

Changing the window or image size mid-calculation may also do bad things.
-- The minibrot finder doesn't seem to very useful with the higher-degree sets, but I'm not sure how hard it would be to tweak it. (Having said that, I just turned it loose on a filament of the power-3 set, and while it won't settle on one minibrot it quite happily took me down to e400 in a few minutes, at which point it seems to be stuck.) --
Update: after a couple of hangs and restarts around e400 I got it chugging away again, and it finally zoomed in on a minibrot at 5e617. (I don't suppose that's a record? I'm happy to share the location, but it would make a really boring movie!) So apparently it does work if you can get deep enough to isolate a minibrot in the first place ...
End update-- Would it be possible to automatically switch off the new checking for the last few frames of a zoom-out? It gets slow when half the frame is occupied by the main 'brot.
Finally, thanks again for the new toys!